BNP and NT-proBNP levels in the blood are used for screening, diagnosis of acute congestive heart failure (CHF) and may be useful to establish prognosis in heart failure, as both markers are typically higher in patients with worse outcome. The plasma concentrations of both BNP and NT-proBNP are also typically increased in patients with asymptomatic or symptomatic left ventricular dysfunction and is associated with coronary artery disease and myocardial ischemia.

Specimen: Serum

Reference Values:

<50 Years Old: <88 pg/ml
50-65 Years Old: <227 pg/ml

Method:

Loinc: 33762-6

In bone physiology, the N-terminal telopeptide (or more formally, amino-terminal collagen crosslinks, and known by the acronym NTX) is a telopeptide that can be used as a biomarker to measure the rate of bone turnover. NTX can be measured in the urine (uNTX) or serum (serum NTX).

Specimen: 0.2 ml Serum

Reference Values:

Pre-menopausal: 6.2-19 nmol BCE
Adult Males: 5.4-24.2 nmol BCE

Method:

Loinc: 21215-9